Physiology and pathology of eosinophils: Recent developments

Over the last century, eosinophils have been regarded ambiguously either as ‘friends’ or ‘foes’. Recent developments greatly enhanced our understanding of role and function in health disease. Pathogenic eosinophilic inflammation can lead to severe diseases various organs, such gastrointestinal tract, airways, heart skin. In a 2-day focus workshop German Society for Allergology Clinical Immunology (DGAKI), state art was discussed practical recommendations diagnosis treatment diseases, with particular on new biologics, anti-interleukin 5 5R, were derived.